STFU && RTFM

When accessing applications through Citrix Web Interface, users sometimes get the following error message:

 
Having researched many possible solutions, the fix I’ve found is this:
 
1: Open Internet Explorer
2: Click Tools > Internet Options
3: On the General tab, click the Delete Files button
4: Restart the browser
 
The cause seems to be that Citrix times out due to not finding the ICA-file because there are too many files in the cache.