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Like in Windows Vista, users don’t usually run programs as administrators, even if they have administrative rights on their computer. While there has been a lot of talk about whether or not User Account Control (UAC) is a good idea (which I think it is, although the implementation in Windows Vista was less than intuitive), most users will have it enabled.
Like in Windows Vista, you can run a program under elevated rights by right-clicking it and selecting “Run as administrator”. This has now been given a keyboard shortcut. Simply hold CTRL+Shift when starting the program, an it will be startet with elevated rights. You will still get the UAC prompt.